Prkar1a^tm1.1Rdf
Targeted Allele Detail

Summary

• Symbol: Prkar1a^tm1.1Rdf
• Name: protein kinase, cAMP dependent regulatory, type I, alpha; targeted mutation 1.1, Riccardo Dalla-Favera
• MGI ID: MGI:5774779
• Synonyms: RIalpha^fl
• Gene: Prkar1a Location: Chr11:109540231-109560482 bp, + strand Genetic Position: Chr11, 72.33 cM
• Alliance: Prkar1a^tm1.1Rdf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:231723
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exon 2 was floxed. The final allele lacks a selection cassette. (J:231723)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkar1a Mutation: 19 strains or lines available

References

• Original: J:231723 Pasqualucci L, et al., PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cells. Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):395-400
• All: 3 reference(s)