Rasal1^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rasal1^em1(IMPC)J
• Name: RAS protein activator like 1 (GAP1 like); endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:5774569
• Synonyms: Rasal1^em1J
• Gene: Rasal1 Location: Chr5:120786877-120817662 bp, + strand Genetic Position: Chr5, 60.63 cM
• Alliance: Rasal1^em1(IMPC)J page
• IMPC: Rasal1 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory using Cas9 and guides with spacer sequences AGGCTAGAGTCTCATATGGT, GAGAATGGGCTGATTCACAG, TGAACCGAATCACATATCAA, and TGGGGGCATGTGTAGACTCT that targeted exon(s) ENSMUSE00001230697.2 ENSMUSE00001252117.2. This resulted in deletion(s) of 481 bp (location: Chr5:120792758-120793238; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rasal1 Mutation: 52 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 3 reference(s)