Crtc2^tm3Mmy
Targeted Allele Detail

Summary

• Symbol: Crtc2^tm3Mmy
• Name: CREB regulated transcription coactivator 2; targeted mutation 3, Marc R Montminy
• MGI ID: MGI:5770689
• Synonyms: Crtc2fl
• Gene: Crtc2 Location: Chr3:90161475-90171432 bp, + strand Genetic Position: Chr3, 39.21 cM, cytoband F2
• Alliance: Crtc2^tm3Mmy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:223039
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites were inserted between exons 1 and 2 and between exons 4 and 5. (J:223039)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Crtc2 Mutation: 29 strains or lines available

References

• Original: J:223039 Hernandez JB, et al., The CREB/CRTC2 pathway modulates autoimmune disease by promoting Th17 differentiation. Nat Commun. 2015;6:7216
• All: 2 reference(s)