Usp18^tm2.1Kpk
Targeted Allele Detail

Summary

• Symbol: Usp18^tm2.1Kpk
• Name: ubiquitin specific peptidase 18; targeted mutation 2.1, Klaus-Peter Knobeloch
• MGI ID: MGI:5767286
• Synonyms: Usp18^fl
• Gene: Usp18 Location: Chr6:121222865-121247876 bp, + strand Genetic Position: Chr6, 57.17 cM, cytoband F
• Alliance: Usp18^tm2.1Kpk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222614
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 3 was floxed. Flp-mediated recombination removed the FRT-flanked neomycin selection cassette inserted upstream of exon 3. (J:222614)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Usp18 Mutation: 23 strains or lines available

References

• Original: J:222614 Goldmann T, et al., USP18 lack in microglia causes destructive interferonopathy of the mouse brain. EMBO J. 2015 Jun 12;34(12):1612-29
• All: 5 reference(s)