Gt(ROSA)26Sor^{tm2(TRIM7)Axbe}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm2(TRIM7)Axbe}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Axel Behrens
• MGI ID: MGI:5763743
• Synonyms: ROSA26-Trim7-IRES-eGFP
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm2(TRIM7)Axbe} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222737
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm2(TRIM7)Axbe} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TRIM7 (81786)

  Trim7

  (MGI:2137353)

• Mutation details: The targeting vector inserted into the locus a floxed STOP cassette, the human cDNA sequence for isoform 1, IRES and EGFP reporter gene. (J:222737)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:222737 Chakraborty A, et al., The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling. Nat Commun. 2015;6:6782
• All: 1 reference(s)