Col16a1^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Col16a1^em1(IMPC)J
• Name: collagen, type XVI, alpha 1; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:5763667
• Synonyms: Col16a1^em1J
• Gene: Col16a1 Location: Chr4:129941638-129993070 bp, + strand Genetic Position: Chr4, 63.43 cM
• Alliance: Col16a1^em1(IMPC)J page
• IMPC: Col16a1 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory using Cas9 and guides with spacer sequences AGAATTCCCGGAGCTCTGCT, AGGTCACTATGAACTCTGGG, GGAGCATTAGGAACTCAGGA, and TCTACCTATTGTCCACCACT that targeted exon(s) ENSMUSE00001259979.2 ENSMUSE00001268302.2. This resulted in deletion(s) of 5 bp (location: Chr4:129945391-129945395; GRCm39), 437 bp (location: Chr4:129945409-129945845; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Col16a1 Mutation: 59 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 4 reference(s)