Drc11^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Drc11^em1(IMPC)J
• Name: dynein regulatory complex subunit 11; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:5763150
• Synonyms: Iqca^em1J
• Gene: Drc11 Location: Chr1:89969854-90081123 bp, - strand Genetic Position: Chr1, 45.08 cM, cytoband C5
• Alliance: Drc11^em1(IMPC)J page
• IMPC: Drc11 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory using Cas9 and guides with spacer sequences ACTCAAACCCCACCACCATG, CGAAGAAGTCTGCAGACAAT, GCACCTTTAACAGAACCCAC, and GTGGATAGCATTCATCCATG that targeted exon(s) ENSMUSE00000541973.3. This resulted in deletion(s) of 4 bp (location: Chr1:90072946-90072949; GRCm39), 524 bp (location: Chr1:90072383-90072906; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Drc11 Mutation: 59 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 3 reference(s)