Acot2^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Acot2^em1(IMPC)J
• Name: acyl-CoA thioesterase 2; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:5763009
• Synonyms: Acot2^em1J
• Gene: Acot2 Location: Chr12:84034635-84040647 bp, + strand Genetic Position: Chr12, 38.99 cM, cytoband D3
• Alliance: Acot2^em1(IMPC)J page
• IMPC: Acot2 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory using Cas9 and guides with spacer sequences CGTTGATGAGGAGATCTGAT, CTGGGTGCTTGAAGACCGGA, GGAAACTGTGGACTCAGCCC, and TATAGACTGTCTCCCAGACA that targeted exon(s) ENSMUSE00001036983.2. This resulted in deletion(s) of 4 bp (location: Chr12:84037167-84037170; GRCm39), 378 bp (location: Chr12:84037187-84037564; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Acot2 Mutation: 18 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 4 reference(s)