Tg(tetO-Edn3,-lacZ)#Kosl
Transgene Detail

Summary

• Symbol: Tg(tetO-Edn3,-lacZ)#Kosl
• Name: transgene insertion, Lidia Kos
• MGI ID: MGI:5762601
• Synonyms: TRE-Edn3-lacZ
• Transgene: Tg(tetO-Edn3,-lacZ)#Kosl Location: unknown
• Alliance: Tg(tetO-Edn3,-lacZ)#Kosl page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(tetO-Edn3,-lacZ)#Kosl expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Edn3 (MGI:95285)

• Mutation details: The 7.5 kb transgene contains a tetracycline response element promoter driving inducible expression of bidirectional CMV minimal promoters directing trnascription of the Edn3 cDNA and lacZ reporter gene. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:129906)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:129906 Garcia RJ, et al., Endothelin 3 induces skin pigmentation in a keratin-driven inducible mouse model. J Invest Dermatol. 2008 Jan;128(1):131-42
• All: 3 reference(s)