H3f3atm1.1Mag
Targeted Allele Detail
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Symbol: |
H3f3atm1.1Mag |
Name: |
H3.3 histone A; targeted mutation 1.1, Terry Magnuson |
MGI ID: |
MGI:5760307 |
Gene: |
H3f3a Location: Chr1:180630125-180641127 bp, - strand Genetic Position: Chr1, 84.46 cM, cytoband D2.3
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Alliance: |
H3f3atm1.1Mag page
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Germline Transmission: |
Earliest citation of germline transmission:
J:225909
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Parent Cell Line: |
E14TG2a.4 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A gene trap targeting vector containing an FRT site, attP site, neomycin resistance cassette, attB site, EGFP, FRT site, and loxP flanked exon 2 was inserted into intron 1 via homologous recombination. Cre-mediated recombination removed the loxP flanked critical first coding exon, exon 2.
(J:225909)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any H3f3a Mutation: |
29 strains or lines available
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Original: |
J:225909 Jang CW, et al., Histone H3.3 maintains genome integrity during mammalian development. Genes Dev. 2015 Jul 1;29(13):1377-92 |
All: |
1 reference(s) |
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