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Epb41l2tm1Tfur
Targeted Allele Detail
Summary
Symbol: Epb41l2tm1Tfur
Name: erythrocyte membrane protein band 4.1 like 2; targeted mutation 1, Takahisa Furukawa
MGI ID: MGI:5759995
Synonyms: 4.1G-
Gene: Epb41l2  Location: Chr10:25235696-25399417 bp, + strand  Genetic Position: Chr10, 12.26 cM
Alliance: Epb41l2tm1Tfur page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:222049
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced exons 2 and 3. Western blot analysis confirmed the absence of protein expression in retinas. (J:222049)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Epb41l2 Mutation:  52 strains or lines available
References
Original:  J:222049 Sanuki R, et al., Protein-4.1G-Mediated Membrane Trafficking Is Essential for Correct Rod Synaptic Location in the Retina and for Normal Visual Function. Cell Rep. 2015 Feb 4;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory