Epb41l2^tm1Tfur
Targeted Allele Detail

Summary

• Symbol: Epb41l2^tm1Tfur
• Name: erythrocyte membrane protein band 4.1 like 2; targeted mutation 1, Takahisa Furukawa
• MGI ID: MGI:5759995
• Synonyms: 4.1G^-
• Gene: Epb41l2 Location: Chr10:25235696-25399417 bp, + strand Genetic Position: Chr10, 12.26 cM
• Alliance: Epb41l2^tm1Tfur page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222049
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced exons 2 and 3. Western blot analysis confirmed the absence of protein expression in retinas. (J:222049)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Epb41l2 Mutation: 52 strains or lines available

References

• Original: J:222049 Sanuki R, et al., Protein-4.1G-Mediated Membrane Trafficking Is Essential for Correct Rod Synaptic Location in the Retina and for Normal Visual Function. Cell Rep. 2015 Feb 4
• All: 2 reference(s)