Cd68^{tm1(EGFP/cre/ERT2)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Cd68^{tm1(EGFP/cre/ERT2)Wtsi}
• Name: CD68 antigen; targeted mutation 1, Wellcome Trust Sanger Institute
• MGI ID: MGI:5755029
• Gene: Cd68 Location: Chr11:69555039-69556979 bp, - strand Genetic Position: Chr11, 42.86 cM
• Alliance: Cd68^{tm1(EGFP/cre/ERT2)Wtsi} page

Mutation origin

• Mutant Cell Line: CEPD0065_2_E04
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: JM8.N4 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: EUCOMMTOOLS

Mutation description

• Allele Type: Targeted (Inducible, Null/knockout, Recombinase, Reporter)
• Inducer: tamoxifen
• Mutations: Insertion, Intragenic deletion
• Cd68^{tm1(EGFP/cre/ERT2)Wtsi} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Cd68 (MGI:88342)

• Mutation details: According to the allele molecular image presented by the International Knockout Mouse Consortium, this allele has exons 2-5 replaced with one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, and a Rox flanked puromycin resistance cassette followed by one loxP site. (J:188991)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cd68 (mouse) Summary of all recombinase alleles driven by Cd68. Comparative matrix view of recombinase activities Alliance mouse Cd68 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd68 Mutation: 34 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 1 reference(s)