Mir378a^tm1.1Hyin
Targeted Allele Detail

Summary

• Symbol: Mir378a^tm1.1Hyin
• Name: microRNA 378a; targeted mutation 1.1, Hao Ying
• MGI ID: MGI:5752625
• Synonyms: 378KO
• Gene: Mir378a Location: Chr18:61530906-61530971 bp, - strand Genetic Position: Chr18, 34.62 cM
• Alliance: Mir378a^tm1.1Hyin page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:225687
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neomycin resistance cassette replaced the pre-microRNA sequence. Cre-mediated recombination removed the selection cassette. (J:225687)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir378a Mutation: 5 strains or lines available

References

• Original: J:225687 Liu W, et al., Hepatic miR-378 targets p110alpha and controls glucose and lipid homeostasis by modulating hepatic insulin signalling. Nat Commun. 2014;5:5684
• All: 3 reference(s)