Klf1^MommeD45
Chemically induced Allele Detail

Summary

• Symbol: Klf1^MommeD45
• Name: Kruppel-like transcription factor 1 (erythroid); modifier of murine metastable epialleles, D45
• MGI ID: MGI:5752592
• Gene: Klf1 Location: Chr8:85628611-85631920 bp, + strand Genetic Position: Chr8, 41.3 cM
• Alliance: Klf1^MommeD45 page

Mutation origin

• Strain of Origin: FVB/N

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced an A-to-G transversion that replaces a histidine with an arginine at position 350 (p.H350R). (J:223531)

Expression

In Mice Carrying this Mutation:

15 assay results 2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Klf1 Mutation: 20 strains or lines available

References

• Original: J:223531 Sorolla A, et al., Identification of novel hypomorphic and null mutations in Klf1 derived from a genetic screen for modifiers of alpha-globin transgene variegation. Genomics. 2015 Feb;105(2):116-22
• All: 2 reference(s)