Agrptm1.1(cre/EGFP)Stei
Targeted Allele Detail
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Symbol: |
Agrptm1.1(cre/EGFP)Stei |
Name: |
agouti related neuropeptide; targeted mutation 1.1, Robert A Steiner |
MGI ID: |
MGI:5752370 |
Synonyms: |
Agrp-CreEGFP |
Gene: |
Agrp Location: Chr8:106293327-106306477 bp, - strand Genetic Position: Chr8, 53.04 cM, cytoband D1-D2
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Alliance: |
Agrptm1.1(cre/EGFP)Stei page
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Allele Type: |
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Targeted (Epitope tag, Recombinase, Reporter) |
Mutation: |
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Insertion
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Agrptm1.1(cre/EGFP)Stei expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: The targeting construct introduced upstream of the start codon a cre recombinase gene fused with EGFP (cre/EGFP), a myc tag, nuclear localization signal at the N-terminus and polyadenulation sequence. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette introduced downstream of the fusion gene.
(J:221577)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Agrp
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Agrp Mutation: |
18 strains or lines available
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Original: |
J:221577 Sanz E, et al., Fertility-regulating Kiss1 neurons arise from hypothalamic POMC-expressing progenitors. J Neurosci. 2015 Apr 8;35(14):5549-56 |
All: |
8 reference(s) |
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