Tg(CD68-Prkaa1*T172D)1Dbrh
Transgene Detail

Summary

• Symbol: Tg(CD68-Prkaa1*T172D)1Dbrh
• Name: transgene insertion 1, DeBroski R Herbert
• MGI ID: MGI:5752355
• Synonyms: CD68-AMPKTG, huCD68-AMPKalpha1^T172D
• Transgene: Tg(CD68-Prkaa1*T172D)1Dbrh Location: unknown
• Alliance: Tg(CD68-Prkaa1*T172D)1Dbrh page

Transgene origin

• Strain of Origin: C57BL/6NTac

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CD68-Prkaa1*T172D)1Dbrh expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  Not Specified	Prkaa1

• Mutation details: The transgene was designed to have the human CD68-IVS-1 promoter (~1 kbp of human CD68 5' flanking sequence with the 83 bp first intron enhancer [IVS-1])direct expression of an AMP-activated protein kinase catalytic alpha 1 cDNA sequence harboring the constitutively active threonine 172 to aspartic acid amino acid substitution (T172D) with amino-terminal myc epitope tag, all followed by a polyadenylation signal. The investigator does not indicate organism source of the expressed gene (e.g. human, mouse, etc.). (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)