Esrrg^tm2.1Rev
Targeted Allele Detail

Summary

• Symbol: Esrrg^tm2.1Rev
• Name: estrogen-related receptor gamma; targeted mutation 2.1, Ronald M Evans
• MGI ID: MGI:5752317
• Synonyms: ERRgamma^flox
• Gene: Esrrg Location: Chr1:187340988-187947082 bp, + strand Genetic Position: Chr1, 91.83 cM, cytoband H5
• Alliance: Esrrg^tm2.1Rev page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:221572
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and a loxP site and FRT flanked selection cassette was inserted downstream of exon 2 via homologous recombination. Flp mediated recombination removed the selection cassette. (J:221572)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Esrrg Mutation: 32 strains or lines available

References

• Original: J:221572 Pei L, et al., Dependence of hippocampal function on ERRgamma-regulated mitochondrial metabolism. Cell Metab. 2015 Apr 7;21(4):628-36
• All: 7 reference(s)