Gt(ROSA)26Sor^tm1(pb)Brd
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm1(pb)Brd
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Allan Bradley
• MGI ID: MGI:5752002
• Synonyms: Rosa26^LSL-PB
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm1(pb)Brd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:220259
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Conditional ready, Transposase)
• Mutation: Insertion
• Mutation details: A construct consisting of a floxed splice acceptor and neo stop cassette followed by a splice acceptor and insect piggyBac transposase was inserted into the locus via homologous recombination. (J:220259)

Tumor Data

List all tumor models in MMHCdb carrying Gt(ROSA)26Sor^tm1(pb)Brd

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:220259 Rad R, et al., A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer. Nat Genet. 2015 Jan;47(1):47-56
• All: 3 reference(s)