Ncor2^tm1.1Anh
Targeted Allele Detail

Summary

• Symbol: Ncor2^tm1.1Anh
• Name: nuclear receptor co-repressor 2; targeted mutation 1.1, Anthony Hollenberg
• MGI ID: MGI:5751854
• Synonyms: SMRT^loxP
• Gene: Ncor2 Location: Chr5:125094217-125256283 bp, - strand Genetic Position: Chr5, 63.96 cM, cytoband F
• Alliance: Ncor2^tm1.1Anh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:224305
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: An FRT- and loxP-flanked neomycin resistance cassette was inserted upsteam of exon 11. An additional loxP site was inserted downstream of exon 11. Flp-mediated recombination removed the selection cassette and left exon 11 floxed. (J:224305)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ncor2 Mutation: 170 strains or lines available

References

• Original: J:224305 Shimizu H, et al., NCoR1 and SMRT play unique roles in thyroid hormone action in vivo. Mol Cell Biol. 2015 Feb;35(3):555-65
• All: 8 reference(s)