Hspa5^tm2Aoe
Targeted Allele Detail

Summary

• Symbol: Hspa5^tm2Aoe
• Name: heat shock protein 5; targeted mutation 2, Tomohiko Aoe
• MGI ID: MGI:5751580
• Synonyms: Bm
• Gene: Hspa5 Location: Chr2:34662102-34666541 bp, + strand Genetic Position: Chr2, 22.94 cM
• Alliance: Hspa5^tm2Aoe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:225297
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutation: Undefined
• The nucleotides encoding the KDEL sequence was replaced with a hemagglutinin (HA) tag. (J:225297)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hspa5 Mutation: 39 strains or lines available

References

• Original: J:225297 Jin H, et al., Late-onset of spinal neurodegeneration in knock-in mice expressing a mutant BiP. PLoS One. 2014;9(11):e112837
• All: 1 reference(s)