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Tg(RNU6-RNAi:Jph2)38Wex
Transgene Detail
Summary
Symbol: Tg(RNU6-RNAi:Jph2)38Wex
Name: transgene insertion 38, Xander Wehrens
MGI ID: MGI:5750921
Synonyms: shJPH2
Transgene: Tg(RNU6-RNAi:Jph2)38Wex  Location: unknown  
Alliance: Tg(RNU6-RNAi:Jph2)38Wex page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Conditional ready, Knockdown)
Mutation:    Insertion
  Tg(RNU6-RNAi:Jph2)38Wex involves 1 genes/genome features (Jph2) View all
 
Mutation detailsThe human promoter disrupted by insertion of a loxP-flanked neo cassette) drives expression of the shRNA targeting Jph2. Two lines were generated (21 and 38) with line 38 selected as the representative line. (J:183751)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:183751 van Oort RJ, et al., Disrupted junctional membrane complexes and hyperactive ryanodine receptors after acute junctophilin knockdown in mice. Circulation. 2011 Mar 8;123(9):979-88
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/20/2026
MGI 6.24
The Jackson Laboratory