Trpm2^tm1Jych
Targeted Allele Detail

Summary

• Symbol: Trpm2^tm1Jych
• Name: transient receptor potential cation channel, subfamily M, member 2; targeted mutation 1.1, Joseph Y Cheung
• MGI ID: MGI:5750872
• Synonyms: Trpm2^fx
• Gene: Trpm2 Location: Chr10:77743556-77805746 bp, - strand Genetic Position: Chr10, 39.72 cM
• Alliance: Trpm2^tm1Jych page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:220747
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exons 21 and 22 were flanked with loxP sites. (J:196475, J:220747)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trpm2 Mutation: 111 strains or lines available

References

• Original: J:220747 Hoffman NE, et al., Ca(2)(+) entry via Trpm2 is essential for cardiac myocyte bioenergetics maintenance. Am J Physiol Heart Circ Physiol. 2015 Mar 15;308(6):H637-50
• All: 6 reference(s)