Rela^tm1Jpy
Targeted Allele Detail

Summary

• Symbol: Rela^tm1Jpy
• Name: Rela proto-oncogene, NFKB subunit; targeted mutation 1, Jianping Ye
• MGI ID: MGI:5750429
• Synonyms: p65^f
• Gene: Rela Location: Chr19:5687511-5698158 bp, + strand Genetic Position: Chr19, 4.34 cM, cytoband B1-3
• Alliance: Rela^tm1Jpy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:220719
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and a floxed neo cassette was inserted downstream of exon 4 via homologous recombination. (J:220719)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rela Mutation: 28 strains or lines available

References

• Original: J:220719 Gao Z, et al., P65 inactivation in adipocytes and macrophages attenuates adipose inflammatory response in lean but not in obese mice. Am J Physiol Endocrinol Metab. 2015 Mar 15;308(6):E496-505
• All: 3 reference(s)