Flt4tm2.1(cre/ERT2)Sgo
Targeted Allele Detail
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Symbol: |
Flt4tm2.1(cre/ERT2)Sgo |
Name: |
FMS-like tyrosine kinase 4; targeted mutation 2.1, Sagrario Ortega |
MGI ID: |
MGI:5750213 |
Synonyms: |
Vegfr3-CreERT2 |
Gene: |
Flt4 Location: Chr11:49500506-49543566 bp, + strand Genetic Position: Chr11, 29.69 cM, cytoband A5-B1
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Alliance: |
Flt4tm2.1(cre/ERT2)Sgo page
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Allele Type: |
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Targeted (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Flt4tm2.1(cre/ERT2)Sgo expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Flt4 (MGI:95561) |
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Mutation details: The targeting vector was constracted by inserting an IRES sequence and inducible cre recombinase gene fusion (cre/ERT2) into the 168 bs downstream of mouse Flt4 gene STOP codon on BAC RP23-445K3. Flp-mediate recombination removed the selection cassette.
(J:228184, J:257380)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Flt4
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Flt4 Mutation: |
76 strains or lines available
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Original: |
J:228184 Stanczuk L, et al., cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels. Cell Rep. 2015 Mar 10; |
All: |
19 reference(s) |
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