Gpr52^em1Zyw
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gpr52^em1Zyw
• Name: G protein-coupled receptor 52; endonuclease-mediated mutation 1, Zhi-Ying Wu
• MGI ID: MGI:5749854
• Gene: Gpr52 Location: Chr1:160403908-160405544 bp, - strand Genetic Position: Chr1, 69.75 cM
• Alliance: Gpr52^em1Zyw page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: TALEN mediated recombination produced an 8 bp deletion (GAATGTGT, 57-64 of the ORF) resulting in a frameshift and premature stop codon. (J:220707)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr52 Mutation: 1 strain or line available

References

• Original: J:220707 Yao Y, et al., A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity. Elife. 2015;4
• All: 1 reference(s)