Abcd2^tm1Sfp
Targeted Allele Detail

Summary

• Symbol: Abcd2^tm1Sfp
• Name: ATP-binding cassette, sub-family D member 2; targeted mutation 1, Sonja Forss-Petter
• MGI ID: MGI:5749733
• Gene: Abcd2 Location: Chr15:91030074-91076002 bp, - strand Genetic Position: Chr15, 46.0 cM, cytoband E-F
• Alliance: Abcd2^tm1Sfp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:220625
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 1,238 bp region including the promotor and most of exon 1 were replaced with a neo cassette via homologous recombination. (J:220625)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Abcd2 Mutation: 53 strains or lines available

References

• Original: J:220625 Muneer Z, et al., Abcd2 is a strong modifier of the metabolic impairments in peritoneal macrophages of ABCD1-deficient mice. PLoS One. 2014;9(9):e108655
• All: 1 reference(s)