Tmem100^tm1.1Xzd
Targeted Allele Detail

Summary

• Symbol: Tmem100^tm1.1Xzd
• Name: transmembrane protein 100; targeted mutation 1.1, Xinzhong Dong
• MGI ID: MGI:5708588
• Synonyms: Tmem100^GFP
• Gene: Tmem100 Location: Chr11:89921174-89927334 bp, + strand Genetic Position: Chr11, 54.75 cM
• Alliance: Tmem100^tm1.1Xzd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:219559
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire coding region in exon 3 was replaced with an EGFP reporter gene and a self-excising neo cassette via homologous recombination. Cre mediated recombination removed the neo cassette. (J:219559)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmem100 Mutation: 16 strains or lines available

References

• Original: J:219559 Weng HJ, et al., Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain. Neuron. 2015 Feb 18;85(4):833-46
• All: 1 reference(s)