Smarca5^tm2.1Ais
Targeted Allele Detail

Summary

• Symbol: Smarca5^tm2.1Ais
• Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5; targeted mutation 2.1, Art I Skoultchi
• MGI ID: MGI:5706633
• Synonyms: Snf2h^exon5fl
• Gene: Smarca5 Location: Chr8:81426572-81466088 bp, - strand Genetic Position: Chr8, 38.41 cM
• Alliance: Smarca5^tm2.1Ais page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:225216
• Parent Cell Line: WW6 (ES Cell)
• Strain of Origin: STOCK 129/Sv and C57BL/6J and SJL

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neomycin resistant cassette with a 5' loxP site was inserted upstream of exon 5. An additional loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the selection cassette and left exon 5 floxed. (J:225216)

Expression

In Mice Carrying this Mutation:

6 assay results 2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Smarca5 Mutation: 49 strains or lines available

References

• Original: J:225216 Alvarez-Saavedra M, et al., Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation. Nat Commun. 2014;5:4181
• All: 13 reference(s)