Gt(ROSA)26Sor^{tm1(tetO-RNAi:Kdm1a)Rosc}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(tetO-RNAi:Kdm1a)Rosc}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Roland Schule
• MGI ID: MGI:5705635
• Synonyms: Lsd1 iKD
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(tetO-RNAi:Kdm1a)Rosc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:206436
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Knockdown)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(tetO-RNAi:Kdm1a)Rosc} involves 1 genes/genome features (Kdm1a) View all
• Mutation details: The targeting vector introduced into the locus a teracycline promoter driving inducible expression of as RNA interference construct targeting Kdm1a. (J:206436)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:206436 Zhu D, et al., Lysine-specific demethylase 1 regulates differentiation onset and migration of trophoblast stem cells. Nat Commun. 2014;5:3174
• All: 1 reference(s)