Engase^tm1Tasuz
Targeted Allele Detail

Summary

• Symbol: Engase^tm1Tasuz
• Name: endo-beta-N-acetylglucosaminidase; targeted mutation 1, Tadashi Suzuki
• MGI ID: MGI:5705598
• Gene: Engase Location: Chr11:118367655-118380035 bp, + strand Genetic Position: Chr11, 83.21 cM
• Alliance: Engase^tm1Tasuz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:217663
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: A genomic region including all of exon 5 was replaced with a pgk-neo cassette via homologous recombination. (J:217663)

Generation of the Engase^tm1Tasuz allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Engase Mutation: 25 strains or lines available

References

• Original: J:217663 Huang C, et al., Endo-beta-N-acetylglucosaminidase forms N-GlcNAc protein aggregates during ER-associated degradation in Ngly1-defective cells. Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1398-403
• All: 5 reference(s)