Ferd3l^tm1Nba
Targeted Allele Detail

Summary

• Symbol: Ferd3l^tm1Nba
• Name: Fer3 like bHLH transcription factor; targeted mutation 1, Nissim Ben-Arie
• MGI ID: MGI:5704437
• Synonyms: Nato3^LacZ
• Gene: Ferd3l Location: Chr12:33978424-33979309 bp, + strand Genetic Position: Chr12, 14.79 cM, cytoband B2
• Alliance: Ferd3l^tm1Nba page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:221299
• Parent Cell Line: iTL BA1 (ES Cell)
• Strain of Origin: (C57BL/6NTac x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ reporter gene with a nuclear localization signal and neomycin resistance cassette replaced the coding sequence. (J:221299)

Expression

In Mice Carrying this Mutation:

42 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ferd3l Mutation: 6 strains or lines available

References

• Original: J:221299 Mansour AA, et al., Nato3 plays an integral role in dorsoventral patterning of the spinal cord by segregating floor plate/p3 fates via Nkx2.2 suppression and Foxa2 maintenance. Development. 2014 Feb;141(3):574-84
• All: 1 reference(s)