Lcn2^tm2Bara
Targeted Allele Detail

Summary

• Symbol: Lcn2^tm2Bara
• Name: lipocalin 2; targeted mutation 2, Jonathan Barasch
• MGI ID: MGI:5703928
• Synonyms: Ngal-Luc2/mC
• Gene: Lcn2 Location: Chr2:32274649-32277751 bp, - strand Genetic Position: Chr2, 22.09 cM, cytoband A3
• Alliance: Lcn2^tm2Bara page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:226161
• Parent Cell Line: KV1 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct introduced into a site between the 5'UTR and the start codon in exon 1 a DiFusion reporter consisting of a luciferase2 gene and mCherry followed by a floxed neomycin resistance cassette. (J:226161)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Lcn2 Mutation: 30 strains or lines available

References

• Original: J:226161 Paragas N, et al., The Ngal reporter mouse detects the response of the kidney to injury in real time. Nat Med. 2011 Feb;17(2):216-22
• All: 2 reference(s)