Smc2^tm1.2Hiran
Targeted Allele Detail

Summary

• Symbol: Smc2^tm1.2Hiran
• Name: structural maintenance of chromosomes 2; targeted mutation 1.2, Tatsuya Hirano
• MGI ID: MGI:5703880
• Synonyms: Smc2^delta
• Gene: Smc2 Location: Chr4:52439243-52488260 bp, + strand Genetic Position: Chr4, 28.31 cM, cytoband B3
• Alliance: Smc2^tm1.2Hiran page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222181
• Parent Cell Line: iTL BA1 (ES Cell)
• Strain of Origin: (C57BL/6NTac x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed the floxed exons 10-12 and the neomycin selection cassette (J:222181)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Smc2 Mutation: 52 strains or lines available

References

• Original: J:222181 Nishide K, et al., Overlapping and non-overlapping functions of condensins I and II in neural stem cell divisions. PLoS Genet. 2014 Dec;10(12):e1004847
• All: 1 reference(s)