Angptl3^tm1Vlcg
Targeted Allele Detail

Summary

• Symbol: Angptl3^tm1Vlcg
• Name: angiopoietin-like 3; targeted mutation 1, Velocigene
• MGI ID: MGI:5701705
• Gene: Angptl3 Location: Chr4:98919191-98926429 bp, + strand Genetic Position: Chr4, 45.6 cM
• Alliance: Angptl3^tm1Vlcg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:226803
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: This allele was generated via homologous recombination using VelociGene (ID VG1425) where exons 1-8 were replaced with LacZ-Hyg cassette. (J:226803)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Angptl3 Mutation: 34 strains or lines available

References

• Original: J:226803 Wang Y, et al., Hepatic ANGPTL3 regulates adipose tissue energy homeostasis. Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11630-5
• All: 4 reference(s)