Tg(Gpr17-icre/ERT2)#Ldim
Transgene Detail

Summary

• Symbol: Tg(Gpr17-icre/ERT2)#Ldim
• Name: transgene insertion, Leda Dimou
• MGI ID: MGI:5701517
• Synonyms: GPR17-iCreERT2
• Transgene: Tg(Gpr17-icre/ERT2)#Ldim Location: unknown
• Alliance: Tg(Gpr17-icre/ERT2)#Ldim page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Gpr17-icre/ERT2)#Ldim expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Gpr17 (MGI:3584514)

• Mutation details: The BAC RP23-237B15 was modified by replacing the coding sequence in exon 2 with an inducible improved cre recombinase gene (icre/ERT2), polyadenylation sequence and stop codon. Two unnamed founders were generated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:227127)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Gpr17 (mouse) Summary of all recombinase alleles driven by Gpr17. Comparative matrix view of recombinase activities Alliance mouse Gpr17 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:227127 Vigano F, et al., GPR17 expressing NG2-Glia: Oligodendrocyte progenitors serving as a reserve pool after injury. Glia. 2016 Feb;64(2):287-99
• All: 1 reference(s)