Tg(Adipoq-LPL)1Fnln
Transgene Detail

Summary

• Symbol: Tg(Adipoq-LPL)1Fnln
• Name: transgene insertion 1, Brian Finlin
• MGI ID: MGI:5699372
• Synonyms: Adipoq-LPL
• Transgene: Tg(Adipoq-LPL)1Fnln Location: unknown
• Alliance: Tg(Adipoq-LPL)1Fnln page

Transgene origin

• Strain of Origin: C3H x C57BL/6

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Adipoq-LPL)1Fnln expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  LPL (4023)

  Lpl	(MGI:96820)

• Mutation details: The AdipoQ-LpL transgene was designed with the murine adiponectin (Adipoq) 5.4-kb promoter driving expression of a FLAG-tagged human lipoprotein lipase (LPL) gene. The transgene is expressed specifically in white adipose tissue. (J:226970)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:226970 Walton RG, et al., Increasing adipocyte lipoprotein lipase improves glucose metabolism in high fat diet-induced obesity. J Biol Chem. 2015 May 1;290(18):11547-56
• All: 1 reference(s)