Epas1^tm2.1Fong
Targeted Allele Detail

Summary

• Symbol: Epas1^tm2.1Fong
• Name: endothelial PAS domain protein 1; targeted mutation 2.1, Guo-Hua Fong
• MGI ID: MGI:5698815
• Synonyms: Hif-2a^f
• Gene: Epas1 Location: Chr17:87061292-87140838 bp, + strand Genetic Position: Chr17, 56.9 cM
• Alliance: Epas1^tm2.1Fong page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199471
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted into intron 2 and a loxP-flanked neomycin selection cassette was inserted into intron 1. The loxP-flanked neomycin selection cassette was removed by Cre-mediated recombination. (J:199471)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Epas1 Mutation: 66 strains or lines available

References

• Original: J:199471 Criscimanna A, et al., PanIN-Specific Regulation of Wnt Signaling by HIF2alpha during Early Pancreatic Tumorigenesis. Cancer Res. 2013 Aug 1;73(15):4781-4790
• All: 4 reference(s)