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Fawq1C57BL/6J
QTL Variant Detail
Summary
QTL variant: Fawq1C57BL/6J
Name: female adrenal weight QTL 1; C57BL/6J
MGI ID: MGI:5698444
QTL: Fawq1  Location: unknown  Genetic Position: Chr3, Syntenic
Variant
origin
Strain of Specimen:  C57BL/6J
Variant
description
Allele Type:    QTL
Inheritance:    Not Specified
Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:170709

Linkage analysis was performed on 64 BXD RI strains (n = 528) to identify QTL associated with adrenal weight in females.

QTL Fawq1 maps to 127 - 129.5 Mb on Chromosome 3 with a peak LOD score of 4.267 in linkage with female adrenal weight. DBA/2J alleles increase adrenal weight at the Fawq1 locus. The protein coding genes Pitx2 and Hnl have been identified as potential Fawq1 candidate genes.

Suggestive QTL for female adrenal weight were mapped to chromosomes 1, 3, 10, and 14.

References
Original:  J:170709 Di Curzio DL, et al., The genetic basis of adrenal gland weight and structure in BXD recombinant inbred mice. Mamm Genome. 2011 Apr;22(3-4):209-34
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory