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Kdm2atm1a(KOMP)Mtok
Targeted Allele Detail
Summary
Symbol: Kdm2atm1a(KOMP)Mtok
Name: lysine (K)-specific demethylase 2A; targeted mutation 1a, Makio Tokunaga
MGI ID: MGI:5697954
Synonyms: Fbxl11neo
Gene: Kdm2a  Location: Chr19:4366172-4448749 bp, - strand  Genetic Position: Chr19, 4.01 cM
Alliance: Kdm2atm1a(KOMP)Mtok page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:217589
Parent Cell Line:  JM8 (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Conditional ready, Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsThe KOMP targeting vector PG00184_Z_8_C04 inserted an FRT site, lacZ reporter gene, loxP site, neomycin resistance cassette, FRT site and loxP site upstream of exon 7 and a third loxP site downstream of exon 9. (J:217589)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kdm2a Mutation:  103 strains or lines available
References
Original:  J:217589 Kawakami E, et al., The histone demethylase Fbxl11/Kdm2a plays an essential role in embryonic development by repressing cell-cycle regulators. Mech Dev. 2015 Feb;135:31-42
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory