Il33^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Il33^tm1.1Arte
• Name: interleukin 33; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:5695359
• Synonyms: Il33^-
• Gene: Il33 Location: Chr19:29902514-29938118 bp, + strand Genetic Position: Chr19, 24.56 cM, cytoband C2
• Alliance: Il33^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:223817
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A loxP site and Frt-floxed neo cassette were inserted in intron 1, with F3-flanked puromycin cassette followed by second loxP site in intron 6. Cre-mediated recombination removed exons 2-6, neomycin and puromycin cassettes. (J:223817)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il33 Mutation: 32 strains or lines available

References

• Original: J:223817 Kearley J, et al., Cigarette smoke silences innate lymphoid cell function and facilitates an exacerbated type I interleukin-33-dependent response to infection. Immunity. 2015 Mar 17;42(3):566-79
• All: 5 reference(s)