Gdf5^bp-6J
Spontaneous Allele Detail

Summary

• Symbol: Gdf5^bp-6J
• Name: growth differentiation factor 5; brachypodism 6 Jackson
• MGI ID: MGI:5695012
• Gene: Gdf5 Location: Chr2:155782943-155787204 bp, - strand Genetic Position: Chr2, 77.26 cM
• Alliance: Gdf5^bp-6J page

Gdf5^bp-6J/Gdf5^bp-6J (on right) showing abnormal front and hind feet and shortened legs compared to control (on left)

Show the 3 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: DBA/2J

Mutation description

• Allele Type: Spontaneous (Not Specified)
• Mutation: Insertion
• Mutation details: This is a spontaneous 2 base pair insertion, CC, between Chromosome 2 position 155,944,953 bp, and 155,944,952 bp in exon 1 (GRCm38) changing the sequence from GAACCCCAGG to GAACCCCCCAGG, which is predicted to alter the amino acid sequence beginning at amino acid 37.
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gdf5 Mutation: 27 strains or lines available

References

• Original: J:226157 Harris BS, et al., brachypodism 6 Jackson. MGI Direct Data Submission. 2015
• All: 1 reference(s)