Tg(Shh-cre/ERT2)#aYjg
Transgene Detail

Summary

• Symbol: Tg(Shh-cre/ERT2)#aYjg
• Name: transgene insertion #a, Yongsu Jeong
• MGI ID: MGI:5692334
• Synonyms: SBE1-CreER^T2
• Transgene: Tg(Shh-cre/ERT2)#aYjg Location: unknown
• Alliance: Tg(Shh-cre/ERT2)#aYjg page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Shh-cre/ERT2)#aYjg expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Shh

• Mutation details: The Shh brain enhancer 1 (SBE1; located within intron 2) drives brain expression of an inducible cre recombinase gene (cre/ERT2). Five expressing founder lines were generated. The unnamed line with expression in the brain and no additional sites is represented by #a. (J:224096)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Shh (species not specified) Summary of all recombinase alleles driven by Shh. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:224096 Lee B, et al., Conditional cell ablation via diphtheria toxin reveals distinct requirements for the basal plate in the regional identity of diencephalic subpopulations. Genesis. 2015 Jun;53(6):356-65
• All: 1 reference(s)