Meikin^tm1Yow
Targeted Allele Detail

Summary

• Symbol: Meikin^tm1Yow
• Name: meiotic kinetochore factor; targeted mutation 1, Yoshinori Watanabe
• MGI ID: MGI:5688710
• Gene: Meikin Location: Chr11:54261478-54317616 bp, + strand Genetic Position: Chr11, 32.13 cM, cytoband B1.3
• Alliance: Meikin^tm1Yow page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:216866
• Parent Cell Line: Baltha1 (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 4 was replaced with a pgk-neo cassette via homologous recombination. (J:216866)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Meikin Mutation: 18 strains or lines available

References

• Original: J:216866 Kim J, et al., Meikin is a conserved regulator of meiosis-I-specific kinetochore function. Nature. 2015 Jan 22;517(7535):466-71
• All: 1 reference(s)