Tg(Ins2-CGA,-FSHB)6Cmal
Transgene Detail

Summary

• Symbol: Tg(Ins2-CGA,-FSHB)6Cmal
• Name: transgene insertion 6, Charles M Allan
• MGI ID: MGI:5661961
• Synonyms: TgFSH^m
• Transgene: Tg(Ins2-CGA,-FSHB)6Cmal Location: unknown
• Alliance: Tg(Ins2-CGA,-FSHB)6Cmal page

Transgene origin

• Strain of Origin: (C3H/HeH x 101/H)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Ins2-CGA,-FSHB)6Cmal expresses 2 genes
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CGA (1081)

  Cga	(MGI:88390)

  human

  FSHB (2488)

  Fshb	(MGI:95582)

• Tg(Ins2-CGA,-FSHB)6Cmal expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Ins2 (24506)

  Ins2	(MGI:96573)

• Mutation details: Two copies of the rat promoter drive pancreas-specific expression of the human sequences each followed by polyadenylation sequences. Lines 1 through 7 were generated in zygotes containing Gnrh1^hpg. (J:129454)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:129454 Allan CM, et al., A novel transgenic model to characterize the specific effects of follicle-stimulating hormone on gonadal physiology in the absence of luteinizing hormone actions. Endocrinology. 2001 Jun;142(6):2213-20
• All: 5 reference(s)