Stk4^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Stk4^tm1Lex
• Name: serine/threonine kinase 4; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:5661514
• Gene: Stk4 Location: Chr2:163916033-163997444 bp, + strand Genetic Position: Chr2, 84.6 cM, cytoband H3
• Alliance: Stk4^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:216318
• Parent Cell Line: Lex-2 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A genomic region including all of exons 3 and 4 was replaced with a beta-geo/puro cassette via homologous recombination. (J:216318)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stk4 Mutation: 75 strains or lines available

References

• Original: J:216318 Salojin KV, et al., Genetic deletion of Mst1 alters T cell function and protects against autoimmunity. PLoS One. 2014;9(5):e98151
• All: 1 reference(s)