Rr37^tm1.1Bulg
Targeted Allele Detail

Summary

• Symbol: Rr37^tm1.1Bulg
• Name: regulatory region 37; targeted mutation 1.1, Michael Bulger
• MGI ID: MGI:5660915
• Synonyms: deltaHS-3'Beta2
• Gene: Rr37 Location: Chr7:103473881-103474053 bp Genetic Position: Chr7, Syntenic
• Alliance: Rr37^tm1.1Bulg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:216256
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Modified regulatory region, Null/knockout)
• Mutations: Insertion, Intergenic deletion
• Mutation details: A loxP site flanked neomycin resistance gene cassette replaced a 316 bp region (+48653-48968) including a regulatory region downstream of Hbb-b2 via homologous recombination. Cre-mediated recombination removed the neo cassette. (J:216256)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr37 Mutation: 0 strains or lines available

References

• Original: J:216256 Cadiz-Rivera B, et al., The chromatin "landscape" of a murine adult beta-globin gene is unaffected by deletion of either the gene promoter or a downstream enhancer. PLoS One. 2014;9(5):e92947
• All: 1 reference(s)