Bcat1^tm1.1Eaa
Targeted Allele Detail

Summary

• Symbol: Bcat1^tm1.1Eaa
• Name: branched chain aminotransferase 1, cytosolic; targeted mutation 1.1, Elitsa A Ananieva
• MGI ID: MGI:5660823
• Gene: Bcat1 Location: Chr6:144939561-145021883 bp, - strand Genetic Position: Chr6, 77.27 cM
• Alliance: Bcat1^tm1.1Eaa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:216027
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A 0.5 kb genomic region including exon 6 was flanked with loxP sites and a floxed neo cassette was inserted via homologous recombination. Cre mediated recombination removed the neo cassette. (J:216027)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcat1 Mutation: 164 strains or lines available

References

• Original: J:216027 Ananieva EA, et al., Cytosolic branched chain aminotransferase (BCATc) regulates mTORC1 signaling and glycolytic metabolism in CD4+ T cells. J Biol Chem. 2014 Jul 4;289(27):18793-804
• All: 1 reference(s)