Gt(ROSA)26Sor^{tm10(CAG-tdTomato,-Tcf4*)Nat}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm10(CAG-tdTomato,-Tcf4*)Nat}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 10, Jeremy Nathans
• MGI ID: MGI:5660287
• Synonyms: R26-LSL-tdT-dnTcf4
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm10(CAG-tdTomato,-Tcf4*)Nat} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:215763
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Dominant negative, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: A construct consisting of a cytomegalovirus/beta-actin promoter/enhancer (CAG), membrane tethered tdTomato, and a triple-myc-2A-dnTcf4 cassette was inserted via homologous recombination. (J:215763)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:215763 Zhou Y, et al., Canonical WNT signaling components in vascular development and barrier formation. J Clin Invest. 2014 Sep 2;124(9):3825-46
• All: 1 reference(s)