Axin1^tm1Scli
Targeted Allele Detail

Summary

• Symbol: Axin1^tm1Scli
• Name: axin 1; targeted mutation 1, Sheng-Cai Lin
• MGI ID: MGI:5659962
• Synonyms: AXIN^F
• Gene: Axin1 Location: Chr17:26357662-26414785 bp, + strand Genetic Position: Chr17, 13.07 cM
• Alliance: Axin1^tm1Scli page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:215643
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: An FRT flanked neo cassette and loxP site were inserted upstream of exon 2 and a loxP site was inserted downstream of exon 2 via homologous recombination. (J:215643)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Axin1 Mutation: 42 strains or lines available

References

• Original: J:215643 Zhang CS, et al., The lysosomal v-ATPase-Ragulator complex is a common activator for AMPK and mTORC1, acting as a switch between catabolism and anabolism. Cell Metab. 2014 Sep 2;20(3):526-40
• All: 6 reference(s)