U2af1l4^tm1.2Tmo
Targeted Allele Detail

Summary

• Symbol: U2af1l4^tm1.2Tmo
• Name: U2 small nuclear RNA auxiliary factor 1-like 4; targeted mutation 1.2, Tarik Moroy
• MGI ID: MGI:5659888
• Gene: U2af1l4 Location: Chr7:30262765-30264789 bp, + strand Genetic Position: Chr7, 18.61 cM
• Alliance: U2af1l4^tm1.2Tmo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:215244
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted downstream of exon 1 and a floxed neo cassette was inserted downstream of exon 7 via homologous recombination. Cre mediated recombination removed the neo cassette and exons 2-7. (J:215244)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any U2af1l4 Mutation: 10 strains or lines available

References

• Original: J:215244 Preussner M, et al., Rhythmic U2af26 alternative splicing controls PERIOD1 stability and the circadian clock in mice. Mol Cell. 2014 May 22;54(4):651-62
• All: 1 reference(s)